c-reactive protein (crp) levels of serum and peritoneal fluid in women with endometriosis
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abstract
background: endometriosis is defined as the existence of endometrial-like tissue outside the uterus. diagnosis of endometriosis is a challenging theme. despite the broad search for innovative laboratory tests and advances in imaging technologies, there are still no easy, non-invasive diagnostic tests available. due to inflammatory process of endometriosis, still c-reactive protein (crp) level may be the target of initial screening. the aim of this study was to investigate crp levels as a marker of inflammatory process in serum and peritoneal fluid of patients with endometriosis. materials and methods: in a case control study, 179 patients with endometriosis (n = 90) and without endometriosis (n = 89) were evaluated. the venous blood samples were obtained from all patients before laparoscopy and the peritoneal fluid samples were collected from pelvis before any manipulation. student’s t-test was applied to compare the parameters between two groups. findings: there was no significant difference between the crp serum level in patients with endometriosis and infertile women without endometriosis. there was a significant difference in peritoneal level of crp between case and control groups (p < 0.05). conclusions: the findings suggested that measurement of this marker in patients’ serum or plasma cannot be used to diagnose endometriosis. it is further recommended that a combination of different markers might be helpful in this regard that could be studied in future.
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Journal title:
iranian journal of nursing and midwifery researchجلد ۱۷، شماره ۲، صفحات ۰-۰
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